FOR UK HEALTHCARE PROFESSIONALS ONLY

For more information about Combisal®, please see the prescribing information.

Prescribing Combisal® pMDI by brand, in place of generic salmeterol/fluticasone combination pMDI prescriptions, could offer the NHS cost savings of up to 55%1*

Combisal Cost Calculator

Use our calculator to find out how much you could save by prescribing Combisal®

How could Combisal® offer significant cost savings to your practice and integrated care system/board (ICS/B)?

  • Salmeterol/fluticasone 25μg/50μg, 25μg/125μg and 25μg/250μg metered dose inhalers are in category C of the England and Wales Drug Tariff.1
  • Due to its lower price than Seretide® (salmeterol/fluticasone) Evohaler, prescribing Combisal® pMDI by brand, in place of generic salmeterol/fluticasone combination pMDI prescriptions, could offer the NHS cost savings of up to 55%1*
  • Combisal® is available from all full and short line wholesalers. 

Bioequivalent Cost Savings

Product (salmeterol/fluticasone)

Age Restriction²

Combisal 25μg/50μg over 4 years
(not severe asthma)
Combisal 25μg/125μg over 12 years
Combisal 25μg/250μg over 12 years
Seretide 50 Evohaler 25μg/50μg over 4 years
(not severe asthma)
Seretide 125 Evohaler 25μg/125μg over 12 years
Seretide 250 Evohaler 25μg/250μg over 12 years
Sirdupla 25μg/125μg over 18 years#
Sirdupla 25μg/250μg over 18 years#
AirFluSal 25μg/125μg over 18 years
AirFluSal 25μg/250μg over 18 years
Aloflute 25μg/125μg over 18 years#
Aloflute 25μg/250μg over 18 years#
Sereflo 25μg/125μg over 18 years
Sereflo 25μg/250μg over 18 years

Strength

Savings vs UK Drug Tariff1

Combisal 25μg/50μg 23%
Combisal 25μg/125μg 55%
Combisal 25μg/250μg 52%

Prescribing Combisal® pMDI by brand, in place of current salmeterol/fluticasone combination pMDIs, could offer the NHS cost savings of up to 55%³*

  • A salmeterol/fluticasone pMDI option for children aged between 4-17 years and for adults well maintained on a low dose (50μg) steroid1**†
  • In line with the brand originator, Combisal® does not contain ethanol.
*up to 55% saving on the cost of Category C salmeterol/fluticasone in the England and Wales Drug Tariff. **The maximum licensed dose of fluticasone propionate delivered by Combisal inhaler in children is 100µg twice daily. Combisal 25/50μg is not appropriate for adults and children with severe asthma ‡salmeterol/fluticasone per metered dose pressurised inhalation, suspension. #Contains alcohol
References: 1) Jan 2023 UK drug tariffs. 2) Summary of Product Characteristics for Combisal, Seretide, Sirdupla, AirFlusal, Aloflute, Sereflo (eMC/MHRA website). 3)  NHS dictionary of medicines and devices (dm+d)
Adverse events should be reported. Reporting forms and information can be found at:

Adverse events should also be reported to Aspire Pharma Ltd on 01730 231148.
www.mhra.gov.uk/yellowcard

COM1010422F1_JAN2023

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